They annihilate all the Venators easily, even with half the numbers.
Total is 20 turbolasers for the Venator, and 91 turbolasers and 64 ion cannons for the ISD. An ISD has 60 heavy TL, 60 ion cannons, plus 6x2 heavy TL, 2x2 heavy ion cannons, 2x4 heavy TL, 3x3 medium TL, 2x1 medium TL. A Venator has 8x2 heavy turbolasers, 2x2 medium TL, 4 proton torpedo tubes and quite a few point defense guns.
Round I is a ISD stomp, the Venators are ridiculously outgunned.